Oxidation of Acetaminophen

acetaminophen

Current HRP/H2O2/APAP Radical Data

New data

HRP/H2O2

Free-Radical Metabolites of Acetaminophen and a Dimethylated Derivative

Volker Fischer, Paul R. West, Laura S. Harman, and Ronald P. Mason.

Environmental Health Perspectives, 1985, 64, pp. 127-137.

PDF here

ACETAMINOPHEN - ENZYMATIC FORMATION OF A TRANSIENT PHENOXYL FREE-RADICAL

West, PR, Harman, LS, Josephy, PD, Mason, RP

Biochemical pharmacology , 1984, Vol.33(18), pp.2933-2936

PDF here

West 1984

Direct electron spin resonance detection of free radical intermediates during the peroxidase catalyzed oxidation of phenacetin metabolites.

Volker Fischer, Laura S. Harman, Paul R. West, and Ronald P. Mason.

"Chem.-Biol. Interactions, 1986, Vol 60, PP. 115-127.

File:APAP radical mason.pdf

Fischer 1986

HRP/H2O2/Acetaminophen analog

Stable Free Radical and Benzoquinone Imine Metabolites of an Acetaminophen Analogue

Volker Fischer and Ronald P. Mason.

Journal of Biological Chemistry, 1984, 259(16), pp. 10284-10288.

here

Fischer, 1984

Fischer, 1984

with GSH

Media:J. Biol. Chem.-1990-Ramakrishna Rao-844-7.pdf

Oxidation Product Analysis

Identification of Acetaminophen Polymerization Products Catalyzed by Horseradish Peroxidase.

David W. Potter$, Dwight W. Miller, and Jack A. Hinson

Journal of Biological Chemistry, 1985 "260(22), pp 12174-12180.

here

Fischer, 1984

Related Phenacetin

http://www.ncbi.nlm.nih.gov/pubmed/3024853