Difference between revisions of "Oxidation of Acetaminophen"
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|-bgcolor=gray | |-bgcolor=gray | ||
!Nuclei!!hyperfine (number spins) | !Nuclei!!hyperfine (number spins) | ||
+ | |- | ||
+ | | bgcolor=gray !Mason!!Mason!!Sturgeon | ||
|- | |- | ||
| N || 0.81 G (1) | | N || 0.81 G (1) |
Revision as of 14:56, 15 July 2018
Current HRP/H2O2/APAP Radical Data
Nuclei | hyperfine (number spins) |
---|---|
bgcolor=gray !Mason!!Mason!!Sturgeon | |
N | 0.81 G (1) |
H, on nitrogen | 1.35 G (1) |
H, ortho | 5.11 G (1) |
H, meta | 0.64 G (1) |
H, methoxy | 1.01 (3) |
HRP/H2O2
- Free-Radical Metabolites of Acetaminophen and a Dimethylated Derivative
- Volker Fischer, Paul R. West, Laura S. Harman, and Ronald P. Mason.
- Environmental Health Perspectives, 1985, 64, pp. 127-137.
- ACETAMINOPHEN - ENZYMATIC FORMATION OF A TRANSIENT PHENOXYL FREE-RADICAL
- West, PR, Harman, LS, Josephy, PD, Mason, RP
- Biochemical pharmacology, 1984, Vol.33(18), pp.2933-2936.
- Direct electron spin resonance detection of free radical intermediates during the peroxidase catalyzed oxidation of phenacetin metabolites.
- Volker Fischer, Laura S. Harman, Paul R. West, and Ronald P. Mason.
- Chem.-Biol. Interactions, 1986, Vol 60, PP. 115-127.
HRP/H2O2/Acetaminophen analog
- Stable Free Radical and Benzoquinone Imine Metabolites of an Acetaminophen Analogue
- Volker Fischer and Ronald P. Mason.
- Journal of Biological Chemistry, 1984, 259(16), pp. 10284-10288.
- here
with GSH
Oxidation Product Analysis
- Identification of Acetaminophen Polymerization Products Catalyzed by Horseradish Peroxidase.
- David W. Potter$, Dwight W. Miller, and Jack A. Hinson
- Journal of Biological Chemistry, 1985 "260(22), pp 12174-12180.
- here