Difference between revisions of "Chlorogenic acid isolation"

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Ground green coffee beans with a blade grinder. Gather the 35 mesh and 60 mesh sized particles. Made 500 mL of 70/30 methanol/water. Shook two 50 mL tubes of .5 g of the green coffee bean particles and 50 mL methanol/water for 1 hour.

Revision as of 19:33, 22 September 2016

Introduction

Chlorogenic acid (CGA) has been said to have beneficial biological properties such as lowering blood pressure and a laxative effect. CGA can be found in several plant like prunes, eggplants, peaches, bamboo and green coffee beans. CGA has been trademarked as Svetol, and is added to many food products like chewing gum and mints.

800px-Chlorogenic-acid-from-CAS-2D-skeletal.png

Chlorogenic acids are being used in health drinks and in high demand, finding a better way to extract the CGA would be big

Proposed Project Description

Extraction chlorogenic acid from green coffee beans. Purification of the crude extract with flash chromatography, and refining the process improving upon it.


References

1):Five ways to Isolate Chlorogenic acid.

2):Microwave assisted extraction with other references to standard solvent extractions.


Current Progress

Sept 2016

9/20 Extraction method

9/22 Ground green coffee beans with a blade grinder. Gather the 35 mesh and 60 mesh sized particles. Made 500 mL of 70/30 methanol/water. Shook two 50 mL tubes of .5 g of the green coffee bean particles and 50 mL methanol/water for 1 hour.