Difference between revisions of "Oxidation of Acetaminophen"

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:'''Direct electron spin resonance detection of free radical intermediates during the peroxidase catalyzed oxidation of phenacetin metabolites.'''
 
:'''Direct electron spin resonance detection of free radical intermediates during the peroxidase catalyzed oxidation of phenacetin metabolites.'''
 
:Volker Fischer, Laura S. Harman, Paul R. West, and Ronald P. Mason.
 
:Volker Fischer, Laura S. Harman, Paul R. West, and Ronald P. Mason.
"Chem.-Biol. Interactions, 1986, Vol 60, PP. 115-127.
+
:"Chem.-Biol. Interactions'', '''1986''', ''Vol 60'', PP. 115-127.
 
:[[Media:APAP radical mason.pdf|PDF here]]
 
:[[Media:APAP radical mason.pdf|PDF here]]
  

Revision as of 13:01, 15 July 2018

acetaminophen

Current HRP/H2O2/APAP Radical Data

New data

HRP/H2O2

West 1984
Fischer 1986
Free-Radical Metabolites of Acetaminophen and a Dimethylated Derivative
Volker Fischer, Paul R. West, Laura S. Harman, and Ronald P. Mason.
Environmental Health Perspectives, 1985, 64, pp. 127-137.
PDF here
ACETAMINOPHEN - ENZYMATIC FORMATION OF A TRANSIENT PHENOXYL FREE-RADICAL
West, PR, Harman, LS, Josephy, PD, Mason, RP
Biochemical pharmacology , 1984, Vol.33(18), pp.2933-2936
PDF here
Direct electron spin resonance detection of free radical intermediates during the peroxidase catalyzed oxidation of phenacetin metabolites.
Volker Fischer, Laura S. Harman, Paul R. West, and Ronald P. Mason.
"Chem.-Biol. Interactions, 1986, Vol 60, PP. 115-127.
PDF here

HRP/H2O2/Acetaminophen analog

Stable Free Radical and Benzoquinone Imine Metabolites of an Acetaminophen Analogue
Volker Fischer and Ronald P. Mason.
Journal of Biological Chemistry, 1984, 259(16), pp. 10284-10288.
here
Fischer, 1984
Fischer, 1984

with GSH

Media:J. Biol. Chem.-1990-Ramakrishna Rao-844-7.pdf

Oxidation Product Analysis

Identification of Acetaminophen Polymerization Products Catalyzed by Horseradish Peroxidase.
David W. Potter$, Dwight W. Miller, and Jack A. Hinson
Journal of Biological Chemistry, 1985 "260(22), pp 12174-12180.
here
Fischer, 1984

Related Phenacetin

http://www.ncbi.nlm.nih.gov/pubmed/3024853