Carley Folluo Chem430 S17

Chemistry Research 430

Spring 2017

Carley Folluo

Senior Chemistry Major

Research Times

Monday 2:30-5:00 PM Tuesday 2:00-3:30 PM

Overflow: Tuesday 3:30-5:00 PM, Thursday 12:00-2:00 PM

CHEM 430-01 = 0.25 credit = 4 hours per week.

Proposed Research Project

General Information

Advisor: Brad Sturgeon

Other research student collaborators: Amanda Hanks (Class of 2015)

Other Research Collaborators: University of Chicago, Dr. Fasano

Proposal

The goal of this project is to develop a method to detect radicals in the crystal structure of teeth created by neutron radiation. Whole human teeth have been obtained from a local dentist, and will be placed in the beam of the neutron generator. After the teeth have been irradiated, counts will be taken with a high purity germanium detector in order to determine the activity of the sample. After the radionuclides have decayed, the teeth will be ground for analysis by electron paramagnetic resonance.

Instruments to be used

Electron Paramagnetic Resonance (EPR)

Neutron Generator

High Purity Germanium (HPGe) Detector

References (2 minimum)

http://www.dartmouth.edu/~eprctr/

http://www.dartmouth.edu/~eprctr/research/tooth_dosimetry.shtml

Barr, D., Sandra S. Eaton, & Gareth R. Eaton. (2008). Workshop on Quantitative EPR. Presented at the 31st Annual International EPR Symposium, Breckenridge, Colorado.

Randall, D. W., Sturgeon, B. E., Ball, J. A., Lorigan, G. A., Chan, M. K., Klein, M. P., … Britt, R. D. (1995). 55Mn ESE-ENDOR of a Mixed Valence Mn(III)Mn(IV) Complex: Comparison with the Mn Cluster of the Photosynthetic Oxygen-Evolving Complex. Journal of the American Chemical Society, 117(47), 11780–11789.

Sturgeon, B. E., Ball, J. A., Randall, D. W., & Britt, R. D. (1994). 55Mn Electron Spin Echo ENDOR of Mn2+ Complexes. The Journal of Physical Chemistry, 98(49), 12871–12883.

Williams, B. B., et al. (2010). Development of in vivo tooth EPR for individual radiation dose estimation and screening. Health Physics, 98(2), 327–338.

Zdravkova, M., et al. (2003). Retrospective Dosimetry after Criticality Accidents Using Low-Frequency EPR: A Study of Whole Human Teeth Irradiated in a Mixed Neutron and Gamma-Radiation Field. Radiation Research, 160(2), 168-173.

Research pledge

I, Carley Folluo, have read the Chem/Bioc 430 course syllabus and understand the general structure and expectations of the research program. The above material was prepared after consultation, and in conjunction with my research advisor.