View source for Carley Folluo Chem430 S17

Chemistry Research 430
:Fall 2016
:[[Carley Folluo]]
:Senior Chemistry Major

==Research Times==
Monday 1-5 PM
: Overflow: Tues/Wed 3-5 PM
: CHEM 430-01 = 0.25 credit = 4 hours per week.

==Proposed Research Project==
===EPR Analysis of Neutron Irradiated Teeth===

===General Information===
:Advisor: Brad Sturgeon
:Other research student collaborators: Amanda Hanks (Class of 2015)
:Other Research Collaborators: Dr. Fasano

===Proposal===
The goal of this project is to develop a method to detect radicals in the crystal structure of teeth created by neutron radiation. Whole human teeth have been obtained from a local dentist, and will be placed in the beam of the neutron generator.  After the teeth have been irradiated, counts will be taken with a high purity germanium detector in order to determine the activity of the sample.  After the radionuclides have decayed, the teeth will be ground for analysis by electron paramagnetic resonance. 

===Instruments to be used===
:Electron Paramagnetic Resonance (EPR)
:Neutron Generator
:High Purity Germanium (HPGe) Detector

===References (2 minimum)===
http://www.dartmouth.edu/~eprctr/
:http://www.dartmouth.edu/~eprctr/research/tooth_dosimetry.shtml

[[Media:Quantitative_EPR_workshop_handout_-_2008.pdf|Barr, D., Sandra S. Eaton, & Gareth R. Eaton. (2008). Workshop on Quantitative EPR. Presented at the 31st Annual International EPR Symposium, Breckenridge, Colorado.]]

Randall, D. W., Sturgeon, B. E., Ball, J. A., Lorigan, G. A., Chan, M. K., Klein, M. P., … Britt, R. D. (1995). 55Mn ESE-ENDOR of a Mixed Valence Mn(III)Mn(IV) Complex: Comparison with the Mn Cluster of the Photosynthetic Oxygen-Evolving Complex. Journal of the American Chemical Society, 117(47), 11780–11789. 

Sturgeon, B. E., Ball, J. A., Randall, D. W., & Britt, R. D. (1994). 55Mn Electron Spin Echo ENDOR of Mn2+ Complexes. The Journal of Physical Chemistry, 98(49), 12871–12883.

[[Media:Development_of_in_Vivo_Tooth_EPR.pdf|Williams, B. B., et al. (2010). Development of in vivo tooth EPR for individual radiation dose estimation and screening. Health Physics, 98(2), 327–338.]]

[[Media:Retrospective_Dosimetry_after_Criticality_Accidents.pdf|Zdravkova, M., et al. (2003). Retrospective Dosimetry after Criticality Accidents Using Low-Frequency EPR: A Study of Whole Human Teeth Irradiated in a Mixed Neutron and Gamma-Radiation Field. Radiation Research, 160(2), 168-173.]]

===Research pledge===
I, Carley Folluo, have read the Chem/Bioc 430 course syllabus and understand the general structure and expectations of the research program. The above material was prepared after consultation, and in conjunction with my research advisor.