YeJun Park Chem430 F16

Chemistry/Biochemistry Research 430

Fall 2016

YeJun Park

Senior Chemistry Major

Research Times

Tuesday 2-5pm/ Research Meeting on Friday after Sci.Sem

section 01 = 0.25 credit = 4 hours per week.

Proposed Research Project

The mechanism behind the antibacterial properties of hop acid investigated with model cell membranes.

General Information

Advisor(s): Audra Sostarecz, Micheal Prinsell

Other research student collaborators: here

Other Research Collaborators: here

Proposal

In summer 2014, I figured that hop acids have some sort of antibacterial ability by disturbing model membrane system.

However, this research was done by the standard hop extract which is mixture of alpha and beta acids.

For this time, based on what Andrea's research from last year. I will be able to alpha and beta acids separately and test which one actually has the antibacterial properties.

To get alpha and beta acid. I will ask help to Micheal whether or not I can get a collaborator, otherwise I will just follow what Andrea did last year based on her notes.

If I get a collaborator, I will focus on getting Langmuir Monolayer Isotherms with different hop acids.

Instruments to be used

Langmuir Trough

References (2 minimum)

Et.al. Marjan Ban Cleemput(Journal of Natural Products, Vol. 72, 2009, No. 6) Et.al. Luke A. Clifton(J. R. Soc. Interface, 2013 10)

Research pledge

I, YeJun Park, have read the Chem/Bioc 430 course syllabus and understand the general structure and expectations of the research program. The above material was prepared after consultation, and in conjunction with my research advisor.