I-TASSER

Welcome the I-TASSER tutorial page, a part of the Monmouth College Wiki.

Introduction

The official link to the I-TASSER website can be found here.

The Wikipedia link can be found here.

(from the Wikipedia page) I-TASSER (Iterative Threading ASSEmbly Refinement) is a bioinformatics method for predicting three-dimensional structure model of protein molecules from amino acid sequences. It detects structure templates from the Protein Data Bank by a technique called fold recognition (or threading). The full-length structure models are constructed by reassembling structural fragments from threading templates using replica exchange Monte Carlo simulations. I-TASSER is one of the most successful protein structure prediction methods in the community-wide CASP experiments.

Activity

Required software:

Access to Jmol download here

I-TASSER result example

RSC Protein Databank