Pauzi Research Spring 2016

Proposed Project Description

We are interested in understanding the enzymatic oxidation of biophenols. We will use the High Performance Liquid Chromatography (HPLC) to collect relevant data.

References

1) Sipe, H. J., Lardinois, O. M., & Mason, R. P. (2014). Free Radical Metabolism of Methyleugenol and Related Compounds. Chemical Research in Toxicology, 27(4), 483–489. http://doi.org/10.1021/tx400256b

2) Chowdhry, B. Z., Ryall, J. P., Dines, T. J., & Mendham, A. P. (2015). Infrared and Raman Spectroscopy of Eugenol, Isoeugenol, and Methyl Eugenol: Conformational Analysis and Vibrational Assignments from Density Functional Theory Calculations of the Anharmonic Fundamentals. The Journal of Physical Chemistry A, 119(46), 11280–11292. http://doi.org/10.1021/acs.jpca.5b07607

3) Mastelić, J., Jerković, I., Blažević, I., Poljak-Blaži, M., Borović, S., Ivančić-Baće, I., … Müller, N. (2008). Comparative Study on the Antioxidant and Biological Activities of Carvacrol, Thymol, and Eugenol Derivatives. Journal of Agricultural and Food Chemistry, 56(11), 3989–3996. http://doi.org/10.1021/jf073272v

4) Ruff, C., Hör, K., Weckerle, B., König, T., & Schreier, P. (2002). Authenticity Assessment of Estragole and Methyl Eugenol by On-Line Gas Chromatography−Isotope Ratio Mass Spectrometry. Journal of Agricultural and Food Chemistry, 50(5), 1028–1031. http://doi.org/10.1021/jf011204h

5) Olbert-Majkut, A., & Wierzejewska, M. (2008). Conformational Study of Eugenol by Density Functional Theory Method and Matrix-Isolation Infrared Spectroscopy. The Journal of Physical Chemistry A, 112(25), 5691–5699

Current Progress

March 2016

I have now been able to collect some chromatograms related to my research project.