Monmouth Microbiome Initiative
"Today (May 13, 2016), the White House Office of Science and Technology Policy (OSTP), in collaboration with Federal agencies and private-sector stakeholders, is announcing the National Microbiome Initiative (NMI). The NMI aims to advance understanding of microbiomes in order to aid in the development of useful applications in areas such as health care, food production, and environmental restoration."
Seminal articles of interest:
A unified initiative to harness Earth’s microbiomes (2015)
- Despite their centrality to life on Earth, we know little about how microbes (Viruses, bacteria, archaea, microscopic fungi, and protists) interact with each other, their hosts, or their environment. Although DNA sequencing technologies have enabled a new view of the ubiquity and diversity of microorganisms, this has mainly yielded snapshots that shed limited light on microbial functions or community dynamics. Given that nearly every habitat and organism hosts a diverse constellation of microorganisms—its “microbiome”— such knowledge could transform our understanding of the world and launch innovations in agriculture, energy, health, the environment, and more (see the photo). We propose an interdisciplinary Unified Microbiome Initiative (UMI) to discover and advance tools to understand and harness the capabilities of Earth’s microbial ecosystems.
- http://science.sciencemag.org/content/350/6260/507
Host-Bacterial Mutualism in the Human Intestine (2005, Highly cited)
- The distal human intestine represents an anaerobic bioreactor programmed with an enormous population of bacteria, dominated by relatively few divisions that are highly diverse at the strain/subspecies level. This microbiota and its collective genomes (microbiome) provide us with genetic and metabolic attributes we have not been required to evolve on our own, including the ability to harvest otherwise inaccessible nutrients. New studies are revealing how the gut microbiota has coevolved with us and how it manipulates and complements our biology in ways that are mutually beneficial. We are also starting to understand how certain keystone members of the microbiota operate to maintain the stability and functional adaptability of this microbial organ.
Proposed Monmouth College involvement
- 1) Biochemistry Research (Sturgeon/Moore/Goach)
- The Hollow Fiber System
- Microbial Biotransformation of Endogenous and Exogenous Biomolecules (Sturgeon/Kieft Summer Research 2016)
- 2) Wellness (J. Braun)
- 3) Modeling (Fasano/M. Sostarecz)
- 4) Educational Garden/Raw Food/Soil (Watson/Engstrom)
- Can we track, then model microbe spread through the "fields" (ex. blueberries, raspberries, strawberries, veggie plots)
Goal: Submit an NSF proposal to fund on-campus research activities.
Education
American Gut Project
- American Gut Project is a part of the Microsetta Project
Researchers
AGP Publications
American Gut: an Open Platform for Citizen Science Microbiome Research, mSystems (2018), 3(3)
Other Videos
Microbiome: Gut Bugs and You | Warren Peters
Food Related Projects
Sour Dough Starter/Bread
Vegetable List
Vegetable List (Wikipedia) Human Gut Bacterial Communities Are Altered by Addition of Cruciferous Vegetables to a Controlled Fruit- and Vegetable-Free Diet (cited 97 times, June 2021)