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Analysis of the Bonding Location between Cannabidiol and DOPE

Introduction

After numerous trials that investigate the interactions between phospholipid 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE) and Cannabidiol (CBD), there have been shown to be interactions that occur that affect the packing of the phospholipid membrane formed by the DOPE molecules. These interactions affect the packing and qualities of the membrane which affects how it will acts in a true cellular membrane. An understanding of this interaction could aid in understanding the affects cannabinoids such as CBD have on biomolecules and biocolecular structures when introduced into the system. This can then be used to improve the pharmaceutical use of this class of molecule.