Rachel Book Chem430 F16

Chemistry/Biochemistry Research 430

Fall 2016

Rachel Book

Sophomore Biochemistry Major

Research Times

Tuesdays from 1-5 pm in the Trough Lab

section 01 = 0.25 credit = 4 hours per week.

General Information

Advisor: Audra Sostarecz

Other research student collaborators: Morgan Gulley, David

Other Research Collaborators: NONE

Proposed Research Project

Langmuir Monolayer and AFM Analysis of a DPPC (currently)

Langmuir-Blodgett Monolayers of Alzheimer's cells. The Langmuir Monolayer technique allows for the analysis of the organization of ampaphilic molecules at an air-water interface and is, therefore, a useful technique for the formation of model cell membranes. Currently I am still learning the process of using the Langmuir-Blodgett Monolayer trough; however, once I have gather the technique, I plan to continue David's research with Alzheimer's Disease.

Instruments to be used

Langmuir-Blodgett Monolayer Trough

ezAFM

References

Ouyang Jiangbo and Lever, A. B. P. "In-trough Langmuir-Blodgett monolayer spectroelectrochemistry of silver (II) tentraneopentoxyphithalocyanine." Journal of Physical Chemistry 95, no. 6 (1991): 2101-2103.

Triulzi, Robert C., Li, Changquing, Naistat, David, Orbulescu, Jhony, and Leblanc, Roger M. "A Two-Dimensional Approach to Study Amyloid B-Peptide Fragment (23-35)." Journal of Physical Chemistry 111 no. 12 (2007): 4661-4666.

Research pledge

I, Rachel Book, have read the Chem/Bioc 430 course syllabus and understand the general structure and expectations of the research program. The above material was prepared after consultation, and in conjunction with my research advisor, Audra Sostarecz.