Difference between revisions of "Acetaminophen"
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[[File:Paracetamol-skeletal.png|200px|thumb|none|APAP]] | [[File:Paracetamol-skeletal.png|200px|thumb|none|APAP]] | ||
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| + | =History of Acetaminophen= | ||
| + | 1893- The white, odorless crystal compound is discovered at the University of Strasburg by Adolf Kussmaul and his team. used it to treat patients with naphthalene | ||
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| + | =Medical Uses= | ||
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| + | =Metabolism and Toxicity= | ||
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| + | =Sources= | ||
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Articles on Acetaminophen toxicity | Articles on Acetaminophen toxicity | ||
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https://www.researchgate.net/publication/5958229_Acetaminophen_paracetamol_is_a_selective_cyclooxygenase-2_inhibitor | https://www.researchgate.net/publication/5958229_Acetaminophen_paracetamol_is_a_selective_cyclooxygenase-2_inhibitor | ||
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Revision as of 00:35, 23 January 2018
Acetaminophen, also known as paracetamol, is a painkiller and fever reducer used to treat mild to moderate pain. Acetaminophen is sold over the counter (OTC) by itself by various companies under various names with the most notable being Tylenol. The drug is also sold OTC co-formulated in many medications including cold medications, menstrual cramping medications, and various other painkillers.
History of Acetaminophen
1893- The white, odorless crystal compound is discovered at the University of Strasburg by Adolf Kussmaul and his team. used it to treat patients with naphthalene
Medical Uses
Metabolism and Toxicity
Sources
Articles on Acetaminophen toxicity
Mechanisms of Acetaminophen-Induced Liver Necrosis
https://ccforum.biomedcentral.com/articles/10.1186/cc1475
http://onlinelibrary.wiley.com/doi/10.1002/hep.20293/full
http://www.sciencedirect.com/science/article/pii/S1544319115308475
Millions of America adults (23 percent) use acetaminophen in a given week. (Slone, JAMA 2002)