Difference between revisions of "Hannah"
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:may also be referred to as an alkenol | :may also be referred to as an alkenol | ||
| − | The basic reaction [[File:tautomerism.png| | + | The basic reaction [[File:tautomerism.png|250px]] |
| + | |||
| + | ==Why Tautomerization Matters== | ||
| + | -Different solvents may change the equilibrium of the keto- and enol- forms | ||
| + | -Tautomers in DNA replication have been hypothesized to contribute to mutagenic mispairings | ||
| + | -A greater diversity of nucleic acid bases [[File:RNA.gif|400px]] | ||
==Keto Acetylacetone== | ==Keto Acetylacetone== | ||
| Line 14: | Line 19: | ||
:PubChem's 3D structure has both oxygens pointing in the same direction (left) while NIST has the oxygens pointing in different directions (right) | :PubChem's 3D structure has both oxygens pointing in the same direction (left) while NIST has the oxygens pointing in different directions (right) | ||
| − | :[[File:Acetylacetone_400×300_3D_Conformer.png|200px]] [[File:ketoacetylacetoneStructure.png| | + | :[[File:Acetylacetone_400×300_3D_Conformer.png|200px]] [[File:ketoacetylacetoneStructure.png|150px]] |
Proton NMR (Hartree-Fock) | Proton NMR (Hartree-Fock) | ||
Revision as of 20:19, 15 April 2021
Tautomers of Acetylacetone (C5H8O2)
Usually the keto tautomer is favored
Keto = ketone
Enol = alcohol
- may also be referred to as an alkenol
The basic reaction 
Why Tautomerization Matters
-Different solvents may change the equilibrium of the keto- and enol- forms
-Tautomers in DNA replication have been hypothesized to contribute to mutagenic mispairings
-A greater diversity of nucleic acid bases 
Keto Acetylacetone
With geometry optimization .png)
- PubChem's 3D structure has both oxygens pointing in the same direction (left) while NIST has the oxygens pointing in different directions (right)
- Error creating thumbnail: File missing
Proton NMR (Hartree-Fock)
Enol Acetylacetone
Proton NMR (Hartree-Fock)
