Difference between revisions of "I-TASSER"

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Welcome the I-TASSER tutorial page, a part of the Monmouth College Wiki.
 
Welcome the I-TASSER tutorial page, a part of the Monmouth College Wiki.
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===Introduction===
  
 
The official link to the I-TASSER website can be found [https://zhanglab.ccmb.med.umich.edu/I-TASSER/ here].
 
The official link to the I-TASSER website can be found [https://zhanglab.ccmb.med.umich.edu/I-TASSER/ here].
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[[File:I-TASSER-pipeline.jpg|800px]]
 
[[File:I-TASSER-pipeline.jpg|800px]]
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===Activity===
  
 
[https://zhanglab.ccmb.med.umich.edu/I-TASSER/example/ I-TASSER result example]
 
[https://zhanglab.ccmb.med.umich.edu/I-TASSER/example/ I-TASSER result example]

Revision as of 14:10, 13 June 2019

Welcome the I-TASSER tutorial page, a part of the Monmouth College Wiki.

Introduction

The official link to the I-TASSER website can be found here.

The Wikipedia link can be found here.

I-TASSER (Iterative Threading ASSEmbly Refinement) is a bioinformatics method for predicting three-dimensional structure model of protein molecules from amino acid sequences.[1] It detects structure templates from the Protein Data Bank by a technique called fold recognition (or threading). The full-length structure models are constructed by reassembling structural fragments from threading templates using replica exchange Monte Carlo simulations. I-TASSER is one of the most successful protein structure prediction methods in the community-wide CASP experiments.

I-TASSER-pipeline.jpg

Activity

I-TASSER result example

References

I-TASSER: a unified platform for automated protein structure and function prediction (2010), Ambrish Roy, Alper Kucukural & Yang Zhang, Nature Protocols Volume 5, pages 725–738