Difference between revisions of "Carley Folluo Chem430 F16"

Latest revision as of 11:31, 6 September 2016

Chemistry Research 430

Fall 2016

Carley Folluo

Senior Chemistry Major

Research Times

Monday 1-5 PM

Overflow: Tues/Wed 3-5 PM

CHEM 430-01 = 0.25 credit = 4 hours per week.

Proposed Research Project

EPR Analysis of Neutron Irradiated Teeth

General Information

Advisor: Brad Sturgeon

Other research student collaborators: Amanda Hanks (Class of 2015)

Other Research Collaborators: Dr. Fasano

Proposal

The goal of this project is to develop a method to detect radicals in the crystal structure of teeth created by neutron radiation. Whole human teeth have been obtained from a local dentist, and will be placed in the beam of the neutron generator. After the teeth have been irradiated, counts will be taken with a high purity germanium detector in order to determine the activity of the sample. After the radionuclides have decayed, the teeth will be ground for analysis by electron paramagnetic resonance.

Instruments to be used

Electron Paramagnetic Resonance (EPR)

Neutron Generator

High Purity Germanium (HPGe) Detector

References (2 minimum)

http://www.dartmouth.edu/~eprctr/

http://www.dartmouth.edu/~eprctr/research/tooth_dosimetry.shtml

Barr, D., Sandra S. Eaton, & Gareth R. Eaton. (2008). Workshop on Quantitative EPR. Presented at the 31st Annual International EPR Symposium, Breckenridge, Colorado.

Randall, D. W., Sturgeon, B. E., Ball, J. A., Lorigan, G. A., Chan, M. K., Klein, M. P., … Britt, R. D. (1995). 55Mn ESE-ENDOR of a Mixed Valence Mn(III)Mn(IV) Complex: Comparison with the Mn Cluster of the Photosynthetic Oxygen-Evolving Complex. Journal of the American Chemical Society, 117(47), 11780–11789.

Sturgeon, B. E., Ball, J. A., Randall, D. W., & Britt, R. D. (1994). 55Mn Electron Spin Echo ENDOR of Mn2+ Complexes. The Journal of Physical Chemistry, 98(49), 12871–12883.

Williams, B. B., et al. (2010). Development of in vivo tooth EPR for individual radiation dose estimation and screening. Health Physics, 98(2), 327–338.

Zdravkova, M., et al. (2003). Retrospective Dosimetry after Criticality Accidents Using Low-Frequency EPR: A Study of Whole Human Teeth Irradiated in a Mixed Neutron and Gamma-Radiation Field. Radiation Research, 160(2), 168-173.

Research pledge

I, Carley Folluo, have read the Chem/Bioc 430 course syllabus and understand the general structure and expectations of the research program. The above material was prepared after consultation, and in conjunction with my research advisor.

@@ Line 1: / Line 1: @@
 Chemistry Research 430
 :Fall 2016
-:Carley Folluo
+:[[Carley Folluo]]
 :Senior Chemistry Major
 ==Research Times==
 Monday 1-5 PM
-: section 01 = 0.25 credit = 4 hours per week.
+: Overflow: Tues/Wed 3-5 PM
+: CHEM 430-01 = 0.25 credit = 4 hours per week.
 ==Proposed Research Project==
-===EPR Analysis of Mn2+ Geometry===
+===EPR Analysis of Neutron Irradiated Teeth===
 ===General Information===
 :Advisor: Brad Sturgeon
 :Other research student collaborators: Amanda Hanks (Class of 2015)
-:Other Research Collaborators:
+:Other Research Collaborators: Dr. Fasano
 ===Proposal===
-The goal of this project is to develop an Electron Paramagnetic Resonance (EPR) teaching method through the execution of various instructional experiments. Samples studied include Mn2+ impurities in MgO, CaO, and SrO complexes and TEMPO in aqueous solution. The MgO, CaO, and SrO complexes are obtained by oxidizing Mg, Ca, and Sr metal. The goal of the instructional experiments is to offer a student an in-depth understanding of how electron spin, d-orbital filling, molecular geometry, nuclear spin, and crystal field affect an EPR spectrum.
+The goal of this project is to develop a method to detect radicals in the crystal structure of teeth created by neutron radiation. Whole human teeth have been obtained from a local dentist, and will be placed in the beam of the neutron generator.  After the teeth have been irradiated, counts will be taken with a high purity germanium detector in order to determine the activity of the sample.  After the radionuclides have decayed, the teeth will be ground for analysis by electron paramagnetic resonance.
 ===Instruments to be used===
-Electron Paramagnetic Resonance (EPR)
+:Electron Paramagnetic Resonance (EPR)
+:Neutron Generator
+:High Purity Germanium (HPGe) Detector
 ===References (2 minimum)===
+http://www.dartmouth.edu/~eprctr/
+:http://www.dartmouth.edu/~eprctr/research/tooth_dosimetry.shtml
+[[Media:Quantitative_EPR_workshop_handout_-_2008.pdf|Barr, D., Sandra S. Eaton, & Gareth R. Eaton. (2008). Workshop on Quantitative EPR. Presented at the 31st Annual International EPR Symposium, Breckenridge, Colorado.]]
 Randall, D. W., Sturgeon, B. E., Ball, J. A., Lorigan, G. A., Chan, M. K., Klein, M. P., … Britt, R. D. (1995). 55Mn ESE-ENDOR of a Mixed Valence Mn(III)Mn(IV) Complex: Comparison with the Mn Cluster of the Photosynthetic Oxygen-Evolving Complex. Journal of the American Chemical Society, 117(47), 11780–11789.
 Sturgeon, B. E., Ball, J. A., Randall, D. W., & Britt, R. D. (1994). 55Mn Electron Spin Echo ENDOR of Mn2+ Complexes. The Journal of Physical Chemistry, 98(49), 12871–12883.
+[[Media:Development_of_in_Vivo_Tooth_EPR.pdf|Williams, B. B., et al. (2010). Development of in vivo tooth EPR for individual radiation dose estimation and screening. Health Physics, 98(2), 327–338.]]
+[[Media:Retrospective_Dosimetry_after_Criticality_Accidents.pdf|Zdravkova, M., et al. (2003). Retrospective Dosimetry after Criticality Accidents Using Low-Frequency EPR: A Study of Whole Human Teeth Irradiated in a Mixed Neutron and Gamma-Radiation Field. Radiation Research, 160(2), 168-173.]]
 ===Research pledge===
 I, Carley Folluo, have read the Chem/Bioc 430 course syllabus and understand the general structure and expectations of the research program. The above material was prepared after consultation, and in conjunction with my research advisor.