Difference between revisions of "Mirna Alhanash Chem430 F16"
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===1. Descriptive information=== | ===1. Descriptive information=== | ||
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| − | ''' | + | '''Determination of Acetaminophen in a Children’s Pain Relief Elixir.''' |
| − | + | Mirna Alhanash | |
| − | + | Research Advisor: Dr. Bradley E. Sturgeon | |
| − | + | Spring/Fall 2016 | |
| + | |||
| + | [[Compact Voltammetry Cell]] | ||
===2. Introduction=== | ===2. Introduction=== | ||
| − | State of the motivation for the project of interest in terms of current literature. When we make reference to current literature, this is where you provide specific reference(s) to this work. This section can be largely copied from an earlier report(s), if they exist, but it is expected that this section is edited to include newly found background information. Note: if the author of previous report(s) is included as a contributor to the project, you may cut and paste text; this is not plagiarism, it is collaboration. | + | |
| + | Acetaminophen is used as a pain reliever and fever reducer. It is the active ingredient in children’s Tylenol which is formulated as a viscous liquid elixir. This research determines the acetaminophen concentration in a sample of elixir using a compact voltammetry cell and applying the cyclic voltammetry which is an electrochemical method. | ||
| + | |||
| + | (State of the motivation for the project of interest in terms of current literature. When we make reference to current literature, this is where you provide specific reference(s) to this work. This section can be largely copied from an earlier report(s), if they exist, but it is expected that this section is edited to include newly found background information. Note: if the author of previous report(s) is included as a contributor to the project, you may cut and paste text; this is not plagiarism, it is collaboration.) | ||
===3. Background from earlier reports=== | ===3. Background from earlier reports=== | ||
| Line 59: | Line 62: | ||
This section describes experiments done during the period covered by the report. Usually, this work will be similar or identical to that described in the prior report, if they exists. Any new experiments will be written up and added to the experimental section. Any experiments preformed under identical conditions need only reference previous reports. | This section describes experiments done during the period covered by the report. Usually, this work will be similar or identical to that described in the prior report, if they exists. Any new experiments will be written up and added to the experimental section. Any experiments preformed under identical conditions need only reference previous reports. | ||
| − | + | ||
::'''Reagents''': ''List reagents used by product number and the source''. | ::'''Reagents''': ''List reagents used by product number and the source''. | ||
| − | + | ''Tylenol Children's Elixir'' | |
| − | + | ''Sigma Aldrich Acetaminophen powder'' | |
| − | ::''' | + | ''Saline Buffer (pH 7.4)'' |
| + | |||
| + | |||
| + | ::'''Wave Driver Compact Voltammetry Cell''': Cyclic voltammograms were produced using After Math software and significant data was exported in the ".CSV" format and then worked up in Igor. | ||
===5. Results=== | ===5. Results=== | ||
This section documents the results of the experiments done during the period covered by the report. Tabulation of data is encouraged; representative spectra presented. | This section documents the results of the experiments done during the period covered by the report. Tabulation of data is encouraged; representative spectra presented. | ||
| − | [[File: | + | |
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| + | [[File:finalresult.jpg|400px|thumb|center|Peak vs Concentration Acetaminophen]] | ||
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| + | The concentration of Acetaminophen in Elixir was determined to be around 140 mg for every 5 ml. | ||
===6. Discussion=== | ===6. Discussion=== | ||
In this section, the student will discuss the results of their work in context of the literature and the results of earlier reports. Questions that have been raised in earlier reports may be addressed here. | In this section, the student will discuss the results of their work in context of the literature and the results of earlier reports. Questions that have been raised in earlier reports may be addressed here. | ||
| + | |||
| + | |||
| + | Percentage of experimental to labeled concentration was 90%(±2%) | ||
===7. Conclusions=== | ===7. Conclusions=== | ||
| Line 84: | Line 98: | ||
===9. Literature references=== | ===9. Literature references=== | ||
| − | + | 1. Determination of Acetaminophen in a Children’s Pain Relief Elixir (n.d.): n. pag. Pine Research Instrumentation, Mar. 2008. Web. | |
| + | |||
| + | 2. Cyclic voltammetry, Peter T. Kissinger and William R. Heineman, Journal of Chemical Education 1983 60 (9), 702, DOI: 10.1021/ed060p702 | ||
===10. Signature=== | ===10. Signature=== | ||
Two copies of the report will be signed and dated and turned in to the Faculty Research Advisor and archived by the Research Coordinator. | Two copies of the report will be signed and dated and turned in to the Faculty Research Advisor and archived by the Research Coordinator. | ||
Latest revision as of 09:27, 17 December 2016
Chemistry/Biochemistry Research 430
- Fall 2016
- Mirna Alhanash
- Senior Chemistry Major
Research Times
T/Thur 2-4 pm
- section 01 = 0.25 credit = 4 hours per week.
Proposed Research Project
Determination of Acetaminophen in a Children's Pain Relief Elixir
General Information
- Advisor: Professor Brad Sturgeon
Proposal
Acetaminophen is used as a pain reliever and fever reducer. It is the active ingredient in children’s Tylenol which is formulated as a viscous liquid elixir. This research determines the acetaminophen concentration in a sample of elixir using a compact voltammetry cell and applying the cyclic voltammetry which is an electrochemical method.
Instruments to be used
WaveNow ™ USB potentiostat with AfterMath ™ software.
References (2 minimum)
1. Determination of Acetaminophen in a Children’s Pain Relief Elixir (n.d.): n. pag. Pine Research Instrumentation, Mar. 2008. Web.
2. Cyclic voltammetry, Peter T. Kissinger and William R. Heineman, Journal of Chemical Education 1983 60 (9), 702, DOI: 10.1021/ed060p702
Research pledge
I, Mirna Alhanash, have read the Chem/Bioc 430 course syllabus and understand the general structure and expectations of the research program. The above material was prepared after consultation, and in conjunction with my research advisor.
Written Report
...from the course syllabus...
- Research students are expected to write a report and submit it to the research coordinator by the last day of regular semester classes. These reports are intended to summarize the data collected over the course of the semester. Since this research course requires you to enroll in at least two semesters of research, two reports will be generated. The first semester report should be considered a work in progress, where as the final report should be a more comprehensive summary of your research project. These reports are necessary since several researchers may work on each project. The report will be organized so that it is clear what material is new and what material is review. When available, research students will be provided with an electronic copy of the latest report on their project. The research student is expected to update and improve the introduction, background, and literature sections with each report. Results that challenge earlier conclusions will be justified in a discussion section. Reports will be submitted in both electronic and hard copy to the Faculty Research Advisor AND Research Coordinator.
1. Descriptive information
Determination of Acetaminophen in a Children’s Pain Relief Elixir.
Mirna Alhanash
Research Advisor: Dr. Bradley E. Sturgeon
Spring/Fall 2016
2. Introduction
Acetaminophen is used as a pain reliever and fever reducer. It is the active ingredient in children’s Tylenol which is formulated as a viscous liquid elixir. This research determines the acetaminophen concentration in a sample of elixir using a compact voltammetry cell and applying the cyclic voltammetry which is an electrochemical method.
(State of the motivation for the project of interest in terms of current literature. When we make reference to current literature, this is where you provide specific reference(s) to this work. This section can be largely copied from an earlier report(s), if they exist, but it is expected that this section is edited to include newly found background information. Note: if the author of previous report(s) is included as a contributor to the project, you may cut and paste text; this is not plagiarism, it is collaboration.)
3. Background from earlier reports
This section will summarize the work reported in earlier reports. If significant results were presented in the most recent report, these results will be summarized and in most cases can be added to that reports background section. This section is included mainly to confirm the current students overall understanding of the project.
4. Experimental
This section describes experiments done during the period covered by the report. Usually, this work will be similar or identical to that described in the prior report, if they exists. Any new experiments will be written up and added to the experimental section. Any experiments preformed under identical conditions need only reference previous reports.
- Reagents: List reagents used by product number and the source.
Tylenol Children's Elixir
Sigma Aldrich Acetaminophen powder
Saline Buffer (pH 7.4)
- Wave Driver Compact Voltammetry Cell: Cyclic voltammograms were produced using After Math software and significant data was exported in the ".CSV" format and then worked up in Igor.
5. Results
This section documents the results of the experiments done during the period covered by the report. Tabulation of data is encouraged; representative spectra presented.
The concentration of Acetaminophen in Elixir was determined to be around 140 mg for every 5 ml.
6. Discussion
In this section, the student will discuss the results of their work in context of the literature and the results of earlier reports. Questions that have been raised in earlier reports may be addressed here.
Percentage of experimental to labeled concentration was 90%(±2%)
7. Conclusions
Restate the findings of this period of research. The statement “No conclusions have been reached,” is an acceptable statement.
8. Future Directions
In this section, the student will discuss possible experiments intended to address unanswered questions or technical problems on the project.
9. Literature references
1. Determination of Acetaminophen in a Children’s Pain Relief Elixir (n.d.): n. pag. Pine Research Instrumentation, Mar. 2008. Web.
2. Cyclic voltammetry, Peter T. Kissinger and William R. Heineman, Journal of Chemical Education 1983 60 (9), 702, DOI: 10.1021/ed060p702
10. Signature
Two copies of the report will be signed and dated and turned in to the Faculty Research Advisor and archived by the Research Coordinator.