Difference between revisions of "Nadia Y. Ayala"
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| + | Curcumin is a secondary plant metabolite of the turmeric herb Curcuma Longa. The term "curcumin" has been used to refer to the bioactive moelcule, but in reality curcumin has three different molecular structures: curcumin I, demethoxycurcumin, and bisdemethoxycurcumin. A review of curcumin studies suggest curcumin has chemotherapeutic, antioxidant, and anti-inflammatory activity, among other uses to be discovered. The current research project aims to successfully isolate and purify curcumin and its derivatives from the plant turmeric. With MeOH under reflux, the curcuminoids will be extracted and subsequently subjected to Flash Chromatography for separation. Once the curcuminoids are separated, NMR data collection will take place to compare the chemical properties of each derivative. | ||
===Instruments to be used=== | ===Instruments to be used=== | ||
Revision as of 21:49, 28 September 2016
Chemistry/Biochemistry Research 430
- Fall 2016
- Nadia Y. Ayala
- Senior Biochemistry Major
Research Times
T/Thur 10am-12pm
- section 01 = 0.25 credit = 4 hours per week.
Proposed Research Project
Turmeric Curcumin Extraction and Analysis
General Information
- Advisor: Bradley Sturgeon
- Other research student collaborators: Stephany Saey
Proposal
Curcumin is a secondary plant metabolite of the turmeric herb Curcuma Longa. The term "curcumin" has been used to refer to the bioactive moelcule, but in reality curcumin has three different molecular structures: curcumin I, demethoxycurcumin, and bisdemethoxycurcumin. A review of curcumin studies suggest curcumin has chemotherapeutic, antioxidant, and anti-inflammatory activity, among other uses to be discovered. The current research project aims to successfully isolate and purify curcumin and its derivatives from the plant turmeric. With MeOH under reflux, the curcuminoids will be extracted and subsequently subjected to Flash Chromatography for separation. Once the curcuminoids are separated, NMR data collection will take place to compare the chemical properties of each derivative.
Instruments to be used
References (2 minimum)
Research pledge
I, Nadia Ayala, have read the Chem/Bioc 430 course syllabus and understand the general structure and expectations of the research program. The above material was prepared after consultation, and in conjunction with my research advisor.