Ian C Salveson - Revision history

Ian Salveson: /* Presentations */

2016-07-21T19:01:32Z

Presentations

Ian Salveson: /* Undergraduate Research Activities */

2016-07-21T18:42:00Z

Undergraduate Research Activities

Bes: /* Personal Information */

2016-06-01T16:44:07Z

Personal Information

Bes: /* Personal Information */

2016-06-01T16:43:48Z

Personal Information

Ian Salveson: /* Projects */

2016-03-21T19:26:08Z

Projects

Ian Salveson: /* Interests */

2016-03-21T19:23:30Z

Interests

Ian Salveson at 18:07, 29 February 2016

2016-02-29T18:07:55Z

Ian Salveson: /* Presentations */

2016-02-29T18:06:50Z

Presentations

Ian Salveson at 18:06, 29 February 2016

2016-02-29T18:06:29Z

Ian Salveson at 15:16, 16 February 2016

2016-02-16T15:16:50Z

← Older revision		Revision as of 19:01, 21 July 2016
Line 30:		Line 30:

	Poster Title: ''Enzymatic Oxidation of Acetaminophen''		Poster Title: ''Enzymatic Oxidation of Acetaminophen''
		+
		+	July 2016: '''Kieft Summer Research Presentations'''
		+
		+	Title: Oxidation of Biophenols

	==Interests==		==Interests==

← Older revision		Revision as of 18:42, 21 July 2016
Line 18:		Line 18:

	Spring 2016: Chem 430 with B. Sturgeon		Spring 2016: Chem 430 with B. Sturgeon
		+
		+	Summer 2016: Kieft Summer Research with Brad Sturgeon (Acetaminophen Oxidation)

	==Presentations==		==Presentations==

@@ Line 9: / Line 9: @@
 ==Personal Information==
-Senoir Chemistry and Classics Major
+Senior Chemistry and Classics Major
 Hometown: St. Charles, IL

@@ Line 9: / Line 9: @@
 ==Personal Information==
-Junior Chemistry and Classics Major
+Senoir Chemistry and Classics Major
 Hometown: St. Charles, IL

@@ Line 41: / Line 41: @@
 ==Projects==
-'''The Mechanism of Acetaminophen Metabolism'''
+[[Acetaminophen Oxidation|'''The Mechanism of Acetaminophen Metabolism''']]
 	Acetaminophen, also known as paracetamol, is a commonly used over-the-counter pain reliever. It is also present in mixtures of prescribed pain medication. Taken in accordance with dosage suggestions, acetaminophen is processed normally by the body and does not cause any adverse side effects; however, taken in excess, acetaminophen can quickly lead to liver failure and death. Acetaminophen alone is responsible for 50% of transplants due to drug related liver injury. Correct identification of the mechanism of acetaminophen induced liver damage is the first step in treating and preventing acetaminophen related liver failure. The currently accepted mechanism for liver injury due to acetaminophen involves the creation of a highly reactive oxidation product NAPQI. However, research has identified the formation of a radical during the enzymatic oxidation of acetaminophen. This has led to a new hypothesis where radicals are continuously forming and combining into polymeric material that would cause a buildup of insoluble material within the liver, preventing blood flow and leading to necrosis. This research will revolve around investigating this new hypothesis by analyzing the products of controlled enzymatic oxidations of acetaminophen using HPLC alongside with NMR and Mass Spectroscopy for the characterization of these products.

@@ Line 31: / Line 31: @@
 ==Interests==
-Water Polo
+-Water Polo
-Cooking
+-Cooking
-Magic: The Gathering
+-Magic: The Gathering
 ==Career Plans==

@@ Line 1: / Line 1: @@
 <!-- ==Personal Information== -->
 <!-- ==Undergraduate Research Activities== -->
@@ Line 11: / Line 6: @@
 <!-- -->
 <!-- -->
-You have reached the personal page of Styles Bitchly.
+You have reached the personal page of Ian Salveson.
 ==Personal Information==

← Older revision		Revision as of 18:06, 29 February 2016
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	Poster Title: ''Enzymatic Oxidation of Acetaminophen''		Poster Title: ''Enzymatic Oxidation of Acetaminophen''
−

	==Interests==		==Interests==

← Older revision		Revision as of 18:06, 29 February 2016
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		+	<!-- Greetings...this text does not show up on the page since it is "hidden" with the surrounding tags -->
		+	<!-- This is the suggested format for current students to organize their information; this is NOT a requirement -->
		+	<!-- To add this structure to your personal wiki page, copy and paste the code below and then remove the "hidden" tags -->
		+	<!-- ...then of course...add your information. Use Mr. Bitchly's text for coding examples...pls add examples to this profile -->
		+
		+	<!-- ==Personal Information== -->
		+	<!-- ==Undergraduate Research Activities== -->
		+	<!-- ==Presentations== -->
		+	<!-- ==Interests== -->
		+	<!-- ==Career Goals== -->
		+	<!-- -->
		+	<!-- -->
		+	You have reached the personal page of Styles Bitchly.
		+
		+	==Personal Information==
		+	Junior Chemistry and Classics Major
		+
		+	Hometown: St. Charles, IL
		+
		+	==Undergraduate Research Activities==
		+
		+	Summer 2015: Kieft Summer Research with Brad Sturgeon (Acetaminophen Oxidation)
		+
		+	Spring 2016: Chem 430 with B. Sturgeon
		+
		+	==Presentations==
		+
		+	June 2014: '''Kieft Summer Research Presentations'''
		+
		+	Title: A Simulated Study of Acetaminophen Induced Liver Injury'''
		+
		+	March 2016: '''251th National ACS Meeting''' San Diego, CA
		+
		+	Poster Title: ''Enzymatic Oxidation of Acetaminophen''
		+
		+
		+	==Interests==
		+
		+	Water Polo
		+	Cooking
		+	Magic: The Gathering
		+
		+	==Career Plans==
		+
		+	College Chemistry Professor
		+
	==Projects==		==Projects==

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	Flash Chromatography(2/15/2016)		Flash Chromatography(2/15/2016)
−
−	~~Blah blah blah~~

← Older revision		Revision as of 15:16, 16 February 2016
Line 1:		Line 1:
		+	==Projects==
		+
	'''The Mechanism of Acetaminophen Metabolism'''		'''The Mechanism of Acetaminophen Metabolism'''

	Acetaminophen, also known as paracetamol, is a commonly used over-the-counter pain reliever. It is also present in mixtures of prescribed pain medication. Taken in accordance with dosage suggestions, acetaminophen is processed normally by the body and does not cause any adverse side effects; however, taken in excess, acetaminophen can quickly lead to liver failure and death. Acetaminophen alone is responsible for 50% of transplants due to drug related liver injury. Correct identification of the mechanism of acetaminophen induced liver damage is the first step in treating and preventing acetaminophen related liver failure. The currently accepted mechanism for liver injury due to acetaminophen involves the creation of a highly reactive oxidation product NAPQI. However, research has identified the formation of a radical during the enzymatic oxidation of acetaminophen. This has led to a new hypothesis where radicals are continuously forming and combining into polymeric material that would cause a buildup of insoluble material within the liver, preventing blood flow and leading to necrosis. This research will revolve around investigating this new hypothesis by analyzing the products of controlled enzymatic oxidations of acetaminophen using HPLC alongside with NMR and Mass Spectroscopy for the characterization of these products.		Acetaminophen, also known as paracetamol, is a commonly used over-the-counter pain reliever. It is also present in mixtures of prescribed pain medication. Taken in accordance with dosage suggestions, acetaminophen is processed normally by the body and does not cause any adverse side effects; however, taken in excess, acetaminophen can quickly lead to liver failure and death. Acetaminophen alone is responsible for 50% of transplants due to drug related liver injury. Correct identification of the mechanism of acetaminophen induced liver damage is the first step in treating and preventing acetaminophen related liver failure. The currently accepted mechanism for liver injury due to acetaminophen involves the creation of a highly reactive oxidation product NAPQI. However, research has identified the formation of a radical during the enzymatic oxidation of acetaminophen. This has led to a new hypothesis where radicals are continuously forming and combining into polymeric material that would cause a buildup of insoluble material within the liver, preventing blood flow and leading to necrosis. This research will revolve around investigating this new hypothesis by analyzing the products of controlled enzymatic oxidations of acetaminophen using HPLC alongside with NMR and Mass Spectroscopy for the characterization of these products.
		+
		+	'''Experiments'''
		+
		+	Flash Chromatography(2/15/2016)
		+
		+	Blah blah blah