Carley Folluo Chem430 S17 - Revision history

Cfolluo: /* References (2 minimum) */

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References (2 minimum)

Cfolluo: /* Research Times */

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Research Times

Cfolluo: /* Instruments to be used */

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Instruments to be used

Cfolluo: /* Proposal */

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Proposal

Cfolluo: /* General Information */

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General Information

Cfolluo: /* Research Times */

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Research Times

Cfolluo at 06:04, 22 January 2017

2017-01-22T06:04:30Z

Cfolluo: Created page with "Chemistry Research 430 :Fall 2016 :Carley Folluo :Senior Chemistry Major ==Research Times== Monday 1-5 PM : Overflow: Tues/Wed 3-5 PM : CHEM 430-01 = 0.25 credit = 4 hour..."

2017-01-22T06:03:06Z

Created page with "Chemistry Research 430 :Fall 2016 :Carley Folluo :Senior Chemistry Major ==Research Times== Monday 1-5 PM : Overflow: Tues/Wed 3-5 PM : CHEM 430-01 = 0.25 credit = 4 hour..."

New page

Chemistry Research 430
:Fall 2016
:[[Carley Folluo]]
:Senior Chemistry Major

==Research Times==
Monday 1-5 PM
: Overflow: Tues/Wed 3-5 PM
: CHEM 430-01 = 0.25 credit = 4 hours per week.

==Proposed Research Project==
===EPR Analysis of Neutron Irradiated Teeth===

===General Information===
:Advisor: Brad Sturgeon
:Other research student collaborators: Amanda Hanks (Class of 2015)
:Other Research Collaborators: Dr. Fasano

===Proposal===
The goal of this project is to develop a method to detect radicals in the crystal structure of teeth created by neutron radiation. Whole human teeth have been obtained from a local dentist, and will be placed in the beam of the neutron generator. After the teeth have been irradiated, counts will be taken with a high purity germanium detector in order to determine the activity of the sample. After the radionuclides have decayed, the teeth will be ground for analysis by electron paramagnetic resonance.

===Instruments to be used===
:Electron Paramagnetic Resonance (EPR)
:Neutron Generator
:High Purity Germanium (HPGe) Detector

===References (2 minimum)===
http://www.dartmouth.edu/~eprctr/
:http://www.dartmouth.edu/~eprctr/research/tooth_dosimetry.shtml

[[Media:Quantitative_EPR_workshop_handout_-_2008.pdf|Barr, D., Sandra S. Eaton, & Gareth R. Eaton. (2008). Workshop on Quantitative EPR. Presented at the 31st Annual International EPR Symposium, Breckenridge, Colorado.]]

Randall, D. W., Sturgeon, B. E., Ball, J. A., Lorigan, G. A., Chan, M. K., Klein, M. P., … Britt, R. D. (1995). 55Mn ESE-ENDOR of a Mixed Valence Mn(III)Mn(IV) Complex: Comparison with the Mn Cluster of the Photosynthetic Oxygen-Evolving Complex. Journal of the American Chemical Society, 117(47), 11780–11789.

Sturgeon, B. E., Ball, J. A., Randall, D. W., & Britt, R. D. (1994). 55Mn Electron Spin Echo ENDOR of Mn2+ Complexes. The Journal of Physical Chemistry, 98(49), 12871–12883.

[[Media:Development_of_in_Vivo_Tooth_EPR.pdf|Williams, B. B., et al. (2010). Development of in vivo tooth EPR for individual radiation dose estimation and screening. Health Physics, 98(2), 327–338.]]

[[Media:Retrospective_Dosimetry_after_Criticality_Accidents.pdf|Zdravkova, M., et al. (2003). Retrospective Dosimetry after Criticality Accidents Using Low-Frequency EPR: A Study of Whole Human Teeth Irradiated in a Mixed Neutron and Gamma-Radiation Field. Radiation Research, 160(2), 168-173.]]

===Research pledge===
I, Carley Folluo, have read the Chem/Bioc 430 course syllabus and understand the general structure and expectations of the research program. The above material was prepared after consultation, and in conjunction with my research advisor.

← Older revision		Revision as of 05:12, 16 February 2017
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	Sturgeon, B. E., Ball, J. A., Randall, D. W., & Britt, R. D. (1994). 55Mn Electron Spin Echo ENDOR of Mn2+ Complexes. The Journal of Physical Chemistry, 98(49), 12871–12883.		Sturgeon, B. E., Ball, J. A., Randall, D. W., & Britt, R. D. (1994). 55Mn Electron Spin Echo ENDOR of Mn2+ Complexes. The Journal of Physical Chemistry, 98(49), 12871–12883.
		+
		+	[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2818093/ Wilcox, D. E., He, X., Gui, J., Ruuge, A. E., Li, H., Williams, B. B., & Swartz, H. M. (2010). Dosimetry Based on EPR Spectral Analysis of Fingernail Clippings. Health Physics, 98(2), 309. http://doi.org/10.1097/HP.0b013e3181b27502]

	[[Media:Development_of_in_Vivo_Tooth_EPR.pdf\|Williams, B. B., et al. (2010). Development of in vivo tooth EPR for individual radiation dose estimation and screening. Health Physics, 98(2), 327–338.]]		[[Media:Development_of_in_Vivo_Tooth_EPR.pdf\|Williams, B. B., et al. (2010). Development of in vivo tooth EPR for individual radiation dose estimation and screening. Health Physics, 98(2), 327–338.]]

@@ Line 5: / Line 5: @@
 ==Research Times==
-Monday 2:30-5:00 PM
+Monday 2:30-4:00 PM
-Tuesday 2:00-3:30 PM
+Tuesday 1:00-3:30 PM
 : Overflow: Tuesday 3:30-5:00 PM, Thursday 12:00-2:00 PM
 : CHEM 430-01 = 0.25 credit = 4 hours per week.

@@ Line 6: / Line 6: @@
 ==Research Times==
 Monday 2:30-5:00 PM
-: Overflow: Tues 3-5 PM
+Tuesday 2:00-3:30 PM
 : CHEM 430-01 = 0.25 credit = 4 hours per week.

@@ Line 23: / Line 23: @@
 ===Instruments to be used===
 :Electron Paramagnetic Resonance (EPR)
-:Neutron Generator
+:Nordion GammaCell Co-60 Irradiation Unit
 ===References (2 minimum)===

@@ Line 19: / Line 19: @@
 ===Proposal===
-The goal of this project is to develop a method to detect radicals in the crystal structure of teeth created by neutron radiation. Whole human teeth have been obtained from a local dentist, and will be placed in the beam of the neutron generator.  After the teeth have been irradiated, counts will be taken with a high purity germanium detector in order to determine the activity of the sample.  After the radionuclides have decayed, the teeth will be ground for analysis by electron paramagnetic resonance.
+The goal of this project is to develop a method to detect radicals formed by radiation in crystalline structures via EPR. In the event of a nuclear accident, radicals produced in teeth, fingernails, and jewelry can provide means to determine the exposure of a patient for triage. Samples will be irradiated a Nordion GammaCell Co-60 Irradiation Unit at 10 cGy/s. Whole human teeth have been obtained from a local dentist, and will be placed into the gamma source.  After the teeth have been irradiated, the teeth will be analyzed via EPR at 410 G. The resultant signal will produce an amplitude which is linearly proportional to the dose administered.
 ===Instruments to be used===

@@ Line 16: / Line 16: @@
 :Advisor: Brad Sturgeon
 :Other research student collaborators: Amanda Hanks (Class of 2015)
-:Other Research Collaborators: Dr. Fasano
+:Other Research Collaborators: University of Chicago, Dr. Fasano
 ===Proposal===

@@ Line 1: / Line 1: @@
 Chemistry Research 430
-:Fall 2016
+:Spring 2017
 :[[Carley Folluo]]
 :Senior Chemistry Major
 ==Research Times==
-Monday 1-5 PM
+Monday 2:30-5:00 PM
-: Overflow: Tues/Wed 3-5 PM
+: Overflow: Tues 3-5 PM
 : CHEM 430-01 = 0.25 credit = 4 hours per week.