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David Thul Chem430 F16

2016-09-30T19:43:19Z

Dthul: /* Research Times */

Chemistry/Biochemistry Research 430
:Fall 2016
:David Thul
:Senior Chemistry Major

==Research Times==
Mon 2-6 pm
: section 01 = 0.25 credit = 4 hours per week.
: section 02 = 0.50 credit = 8 hours per week.

==Proposed Research Project==
===Enter Project Title here===
Insertion of Amyloid Beta into anionic membranes
===General Information===
:Advisor: Audra Sostarecz
:Other research student collaborators: here
:Other Research Collaborators: here

===Proposal===
Looking at binding patterns of amyloid beta (AB) into anionic membranes. With varying the anionic conditions of synthetic membranes, based on the relative concentrations of DPPC and DPPS, the insertion rate into the lipids tail groups and the binding pattern on the head groups will be studied. It is expected to see that binding and insertion patterns be more significant with an increasing anionic concentration. Previous research here has looked at domain characterization of DPPC/DPPS/cholesterol, as well as the binding characteristics of AB in DPPC model membranes. This research aims to establish a stable platform for further researchers, establishing a relationship between membrane charge and AB binding/insertion interactions.

===Instruments to be used===
Monolayer Trough: isotherm, compression analysis.
AFM.
Fluorescence spectroscopy.

===References (2 minimum)===

===Research pledge===
I, David Thul, have read the Chem/Bioc 430 course syllabus and understand the general structure and expectations of the research program. The above material was prepared after consultation, and in conjunction with my research advisor.

David Thul Chem430 F16

2016-09-30T19:42:50Z

Dthul: /* Instruments to be used */

Chemistry/Biochemistry Research 430
:Fall 2016
:David Thul
:Senior Chemistry Major

==Research Times==
Mon 2-4 pm
: section 01 = 0.25 credit = 4 hours per week.
: section 02 = 0.50 credit = 8 hours per week.

==Proposed Research Project==
===Enter Project Title here===
Insertion of Amyloid Beta into anionic membranes
===General Information===
:Advisor: Audra Sostarecz
:Other research student collaborators: here
:Other Research Collaborators: here

===Proposal===
Looking at binding patterns of amyloid beta (AB) into anionic membranes. With varying the anionic conditions of synthetic membranes, based on the relative concentrations of DPPC and DPPS, the insertion rate into the lipids tail groups and the binding pattern on the head groups will be studied. It is expected to see that binding and insertion patterns be more significant with an increasing anionic concentration. Previous research here has looked at domain characterization of DPPC/DPPS/cholesterol, as well as the binding characteristics of AB in DPPC model membranes. This research aims to establish a stable platform for further researchers, establishing a relationship between membrane charge and AB binding/insertion interactions.

===Instruments to be used===
Monolayer Trough: isotherm, compression analysis.
AFM.
Fluorescence spectroscopy.

===References (2 minimum)===

===Research pledge===
I, David Thul, have read the Chem/Bioc 430 course syllabus and understand the general structure and expectations of the research program. The above material was prepared after consultation, and in conjunction with my research advisor.

David Thul Chem430 F16

2016-09-30T19:41:42Z

Dthul: /* Proposal */

Chemistry/Biochemistry Research 430
:Fall 2016
:David Thul
:Senior Chemistry Major

==Research Times==
Mon 2-4 pm
: section 01 = 0.25 credit = 4 hours per week.
: section 02 = 0.50 credit = 8 hours per week.

==Proposed Research Project==
===Enter Project Title here===
Insertion of Amyloid Beta into anionic membranes
===General Information===
:Advisor: Audra Sostarecz
:Other research student collaborators: here
:Other Research Collaborators: here

===Proposal===
Looking at binding patterns of amyloid beta (AB) into anionic membranes. With varying the anionic conditions of synthetic membranes, based on the relative concentrations of DPPC and DPPS, the insertion rate into the lipids tail groups and the binding pattern on the head groups will be studied. It is expected to see that binding and insertion patterns be more significant with an increasing anionic concentration. Previous research here has looked at domain characterization of DPPC/DPPS/cholesterol, as well as the binding characteristics of AB in DPPC model membranes. This research aims to establish a stable platform for further researchers, establishing a relationship between membrane charge and AB binding/insertion interactions.

===Instruments to be used===
Monolayer Trough
AFM
Fluorescence

===References (2 minimum)===

===Research pledge===
I, David Thul, have read the Chem/Bioc 430 course syllabus and understand the general structure and expectations of the research program. The above material was prepared after consultation, and in conjunction with my research advisor.

David Thul Chem430 F16

2016-09-28T14:56:59Z

Dthul: /* Instruments to be used */

David Thul Chem430 F16

2016-09-28T14:55:30Z

Dthul:

David Thul Chem430 F16

2016-09-28T14:55:04Z

Dthul: Created page with "Chemistry/Biochemistry Research 430 :Fall 2016 :David Thul :Senior Chemistry Major ==Research Times== Mon 2-4 pm : section 01 = 0.25 credit = 4 hours per week. : section 02 =..."